Target Markets & Applications
Significantly improving aesthetic outcomes
Not FDA cleared for commercial use.
It is estimated that there are almost 14 million surgical and non-surgical cosmetic procedures performed in the U.S. annually (ASAPS 2016). Recros Medica is developing disruptive technologies that may blend the results of some surgeries with the quick recovery of minimally invasive procedures.
One of the most visible signs of aging is the development of loose, disfigured or discolored skin. This lifelong process may become evident as early as the third or fourth decade of life and progressively worsens with the passage of time.
The frequency and negative societal impact of these aesthetic conditions has prompted the development of surgical procedures such as facelifts, scar revisions and brachioplasties (upper arms); and many technologies targeting regrettable tattoos. While these procedures have been widely used, surgical procedures may result in post-operative pain, scarring and other complications; while tattoo removal has so far been an inefficient procedure with modest results from existing technologies.
Potential Clinical Applications
Historically loose skin has been treated with electromagnetic medical devices that create a reverse thermal gradient. However, these devices have had variable success to reduce skin laxity without surgery.
We believe that the Company’s RFR platform will significantly improve aesthetic outcomes for focal aesthetic contouring by removing excess skin without the appearance of visible scarring. Targeted areas of the body that are poorly served by existing technologies and surgery will be the initial focus for the Company. Rotational Fractional Resection should enhance aesthetic outcomes by reducing the complexity, repeated treatments and recovery period of currently available procedures.
Finally, because of the safety features and potential for reproducible results, RFR should expand the number of medical aesthetic physicians that can successfully treat these patients.
According to a recent study, 30% of all American adults now have tattoos; and 29% of those tattooed now regret getting tattoos (Harris Poll 2015). Lasers are the primary technology used today for the removal of tattoos. However, another recent study (N=397) reported that only 47% of those undergoing laser treatment with 10 treatment sessions reported a successful outcome (Consumer Reports).
RFR tattoo removal will probably be achieved with 4 to 5 successive treatments conducted about one month apart. This approach to tattoo removal could be faster and more complete than any other treatment option.
Market analysts predict that with effective technologies, tattoo removal could be one of the largest markets in aesthetic dermatology in the future. We believe that the ease of use, fewer treatment sessions, lower cost and enhanced efficacy for dye removal will drive the use of more effective technologies for tattoo removal.
There are numerous causes for the formation of scars. Scars are caused by either trauma or a surgical procedure which results in the formation of scar tissue. Scars are often irregularly formed and are often further demarcated by a pigmentary difference from the adjacent normal skin. Scar revision is currently conducted utilizing cryotherapy, pressure therapy, surgery or lasers. A variety of different lasers are used to smooth, flatten or remove the abnormal color of the scar; and there were over 170,000 scar revision procedures performed in the U.S. in 2014 (Lim et al, PRS 2014 Feb 133(2): 398-405).
Excessive scarring can also occur from the excision of a scar lesion. Many of these scars are unsightly due to irregular pigmentation from a shaved lesion excision. Fractional scar revision should reduce the visual impact of these scars by reducing the surface area of these unsightly deformities. The potential also exists to shorten incisions required to elliptically excise lesions of the skin. With this application, each end of the excision will be fractionally resected instead of being lengthened by elliptical excision to avoid a “dog ear” skin redundancy.
The Company expects that the multi-scalpet array will provide medical aesthetic physicians with an effective and less invasive alternative that can be performed in the office setting.